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Topamax® & Stevens-Johnson Syndrome (SJS)

January 4, 2021

First discovered in 1979, Topamax® (topiramate) is an epilepsy medication available via prescription and produced by Ortho-McNeil Nuerologics and Noramac, Inc. (both of which are subsidiaries of Johnson & Johnson).


In addition to being an effective anticonvulsant medication, researchers are currently investigating whether Topamax® is appropriate for the treatment of:

  • bipolar disorder
  • bulimia and compulsive eating disorders
  • nerve-related pain
  • obesity
  • obsessive-compulsive disorder
  • smoking cessation, alcoholism and cocaine dependence

Potential Injuries and Side Effects

Regardless of its healing properties, Topamax® may have the potential to cause a range of severe side effects. Among the potential side effects of Topamax® are rickets, glaucoma, suicidal thoughts/actions and Stevens-Johnson syndrome. Given such risks, it's crucial that Topamax® patients are aware of the possible side effects, as well as the symptoms of these SJS side effects, so they know when to seek emergency medical care.

If you or a loved one has been diagnosed with a serious condition, such as Stevens-Johnson syndrome, after taking Topamax®, you should know you may be able to seek compensation for your losses. Our Stevens-Johnson syndrome attorneys may be able to help you obtain justice for the damages you've incurred. To find out how, contact us today.

Understanding Stevens-Johnson Syndrome

Debilitating and potentially deadly, Stevens-Johnson syndrome is a serious skin condition that causes the skin's top layer, the epidermis, to detach from the other layers, die off and shed (slough) from the body. During this process, Stevens-Johnson syndrome may also cause severe inflammation of the body's mucous membranes, along with:

  • arrhythmia
  • conjunctivitis
  • coughing
  • diarrhea and vomiting
  • fever and headaches
  • hypotension (excessively lower blood pressure)
  • seizures and/or coma

Patients who are taking Topamax® and begin developing any combination of the above symptoms should seek immediate medical care for a thorough exam and a proper diagnosis of Stevens-Johnson Syndrome. The earlier Stevens-Johnson syndrome is identified and treated, the better chances patients will have of surviving.

The more severe cases are referred to as toxic epidermal necrolysis.

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